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Sunday sees the inaugural Wear-Tyne derby since 2024, but which side will celebrate – the Black Cats or the Magpies?
"Throughout the majority of last season, you couldn't have imagined the Wearside club earning promotion and challenging with Eddie Howe's Newcastle, much less being above them in the table," commented analyst Chris Sutton.
"Things are very different now, and the way Sunderland play makes me think they've got a genuine opportunity."
The analyst is providing predictions for all 380 Premier League games this campaign, against artificial intelligence, the public and a variety of guests.
For week 16, he faces off against England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the England's esports team – the Football Association's official esports team – at the gaming title digital Euros finals tournament, which takes place at Twickenham Stadium on Saturday.
You can watch Uefa's video platform, Instagram Live and TikTok channels, as well as EA Sports FC Twitch and its YouTube counterpart and England's Twitch.
What are your thoughts with their scores? Share your own predictions below.
The fan-favourite scoreline chosen for each game is displayed on the leaderboards at the bottom of this page.
A correct result (picking a win, draw or defeat) is worth ten points. The exact score earns 40 points.
Ray, who competes for his club side and Manchester City as well as England, is entering the fray at the eEuros finals after getting through the qualifying.
A group of eight will fly the flag at the finals in a knockout format, competing for a substantial cash prize and a highly sought-after spot in the FC Pro World Championship Play-Ins, with Denmark's Anders Vejrgang defending the title he won last year.
"I am feeling really good for it," Ray said. "I've got a really good coach alongside me and training has been going well.
"Representing your country is always an honour to play for your country. Of course when you are younger, you fantasise about doing it as an professional footballer, but when you go into this field and there is an opportunity to represent England, wearing the Three Lions is something unique.
"I defeated Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd not previously defeated him in a tournament before.
"I believe he is the number one in the world so beating him in a tournament like this just provides a huge surge of confidence."
Premier League Forecasts
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The London club were outstanding against Arsenal at the end of November, when they got a draw after going down to 10 men, and it seemed they've turned a corner, they could possibly be challengers for the crown.
However, since that game, however, they were overpowered by Leeds, looked flat against Bournemouth and this week got beaten by Atalanta in the Champions League.
So head coach Enzo Maresca desperately requires a win here to restore momentum, but it won't be easy because the Merseyside club are such a dangerous team.
Their key midfielders are playing exceptionally and they have got a bit of momentum at the moment.
On form you would likely back Everton, while the most sensible prediction would probably be a draw, but I am not going to be sensible.
They have not given me any compelling evidence to back them recently, but I just have a feeling Chelsea will take this one because they are at home and they are due a win.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'm attending this game and it will be fascinating to see what we get from Liverpool.
I am really pleased for Reds boss Arne Slot to get such a great win at Inter Milan on Tuesday after all the stuff with Mohamed Salah this week.
Slot should not have to put up with that distraction. I know Salah has been a legend for Liverpool but fundamentally Slot just wants to win games and there is no ulterior motive in his team selection.
They changed their tactical setup against Inter and went with a midfield diamond and two up top.
The media is going to be talking about whether Salah is included for this game, but the only way he is going to be reintegrated is if he says sorry.
Slot's primary concern will be on winning this game, but it is a difficult fixture.
It's fair to say it is the same for most teams but I find Brighton so unpredictable. I always feel they have got a goal in them, but they are vulnerable at the back too.
The Merseysiders need to get back to stringing wins together, but I am not sure how much their exertions at the San Siro will have affected their stamina.
I have whacked a couple of Brighton players in my FPL team, so they will likely do poorly - but I do fancy get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the opportunity to rest while Newcastle had to battle intensely against Bayer Leverkusen on Wednesday, only to concede a late equaliser late on.
Aside from their excellent performance against Everton a couple of weeks ago, Newcastle's away form has been poor, especially straight after they've played in the Champions League.
It is anticipated that that trend to continue on Sunday, and their tiredness is likely to be a key element in how this game goes because of Sunderland's high press.
Their match against Arsenal demonstrated how relentless Regis le Bris's side are. They overpowered the Gunners, and it was incredible to watch.
Everyone talks about how Granit Xhaka has been phenomenal for the Black Cats, and he has been brilliant, but Noah Sadiki, who plays next to him, has also been one of the best acquisitions and warrants praise too.
All signs point to this being the best game|most exciting fixture